WebNoushin Brealey. Effect of moderate hepatic impairment (MHI) on umeclidinium (UMEC) and vilanterol (VI) pharmacokinetics (PK) By Rashmi Mehta, Kelly Hardes, Dennis Kelleher, … WebNoushin Brealey's 48 research works with 1,378 citations and 5,871 reads, including: Inhaled glucocorticoid-induced metabolome changes in asthma Noushin Brealey's research while …
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WebMaggie Tabberer 1 , David A Lomas 2 , Ruby Birk 3 , Noushin Brealey 3 , Chang-Qing Zhu 4 , Steve Pascoe 5 , Nicholas Locantore 5 , David A Lipson 5 6 Affiliations 1 Value Evidence and Outcomes, GSK, Stockley Park, UK. [email protected]. WebNoushin Brealey Clinical Unit Cambridge (CUC) Medical Director & Senior Director, Discovery Medicine Physician Watford, England, United Kingdom …
WebJan 8, 2024 · Brealey is an employee of GSK/holds shares. C.-Q. Zhu is an employee of GSK/holds shares. S. Pascoe is an employee of GSK/holds shares. N. Locantore is an employee of GSK/holds shares. ... Ruby Birk & Noushin Brealey. Clinical Statistics, GSK, Stockley Park, UK. Chang-Qing Zhu. Respiratory Research and Development, GSK, King of … WebJan 25, 2024 · GSK study CTT200812; ClinicalTrials.gov NCT02729051 (submitted 31 March 2016). ... Noushin Brealey 2 , Afisi S Ismaila 3 4 , Chang-Qing Zhu 2 , David A Lipson 5 6 Affiliations 1 University of Notre Dame, Fremantle, WA, Australia. 2 GSK, Stockley Park West, Uxbridge, Middlesex, UK. 3 GSK, Collegeville, PA, USA. 4 Department ...
WebDennis Kelleher 1 , Lee Tombs 2 , Andrew Preece 3 , Noushin Brealey 3 , Rashmi Mehta 4 Affiliations 1 Respiratory Medicines Development Center, GlaxoSmithKline, Research Triangle Park, USA. Electronic address: [email protected]. 2 Synergy, Statistics and Programming, Slough, Berkshire, UK. WebSep 28, 2024 · We investigated whether these attributes improve the therapeutic index (TI), defined as systemic activity to topical efficacy ratio. In this escalating dose, randomised, incomplete-block, 2-period cross-over study (GSK study 203162, NCT02991859), 54 asthmatic subjects were randomised to one or two of four treatment periods.
WebRationale: Current GOLD strategy document positions both combination regimens of inhaled corticosteroid plus a long-acting β2-agonist [i.e. ICS/LABA] and long-acting muscarinic antagonist plus LABA [i.e. LAMA/LABA] for symptomatic patients with recurrent exacerbations. Methods: The InforMing the PAthway of COPD Treatment (IMPACT) study …
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