This protein has been shown to stimulate the proliferation of T cells, trigger apoptosis of various tumor cells and play a role in vascular normalisation processes. This protein is also reported to prevent tumor necrosis factor alpha-mediated apoptosis in primary hepatocytes. Meer weergeven LIGHT, also known as tumor necrosis factor superfamily member 14 (TNFSF14), is a secreted protein of the TNF superfamily. It is recognized by herpesvirus entry mediator (HVEM), as well as decoy receptor 3 Meer weergeven LIGHT stands for "homologous to lymphotoxin, exhibits inducible expression and competes with HSV glycoprotein D for binding to herpesvirus entry mediator, a receptor … Meer weergeven LIGHT has been shown to interact with TNFRSF14, TNFRSF6B, BIRC2, TRAF2 and TRAF3. Meer weergeven • Yang D, Zhai Y, Zhang M (2003). "LIGHT, a new member of the TNF superfamily". Journal of Biological Regulators and Homeostatic Agents. 16 (3): 206–10. PMID 12456019. • Bénichou S, Benmerah A (January 2003). "[The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the endocytosis pathway]" Meer weergeven The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry … Meer weergeven Similar to how CD4 is the primary mediating receptor in HIV infection, the HSV glycoprotein (gD) binds to the HVEM receptor which is demanded by TNFSF14/LIGHT lowering the ability for LIGHT to activate the NFκB pathway. NFκB is a survival … Meer weergeven • TNFSF14+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from the United States National Library of Medicine Meer weergeven WebThe extracellular domain of human LIGHT (aa 89-240) is fused at the N-terminus to a linker peptide (10 aa) and a FLAG®-tag. UniProt ID: O43557 Concentration: 0.1mg/ml after reconstitution. Formulation: Lyophilized. Contains PBS. Purity: ≥95% (SDS-PAGE) Endotoxin Content: 0.1EU/µg purified protein (LAL test; Associates of Cape Cod).

NF-light Serum ELISA - UmanDiagnostics

WebThe extracellular domain of human LIGHT (aa 89-240) is fused at the N-terminus to a linker peptide (10 aa) and a FLAG®-tag. UniProt ID: O43557 Concentration: 0.1mg/ml after … WebHuman LIGHT is a type II membrane protein that is a member of the TNF superfamily. LIGHT is an acronym which stands for "is homologous to l ymphotoxins, exhibits i nducible expression, and competes with HSV g lycoprotein D for H VEM, a receptor expressed by T lymphocytes". LIGHT has also been called HVEM-L and LT-gamma . two layer bike storage

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Web29 mrt. 2013 · LIGHT/TNFSF14 is a member of the tumor necrosis factor ligand superfamily, which plays important roles in inflammatory and immune responses. In this study, the cDNA of mefugu (Takifugu obscures) LIGHT (designated as fLIGHT) was amplified from spleen by reverse transcription polymerase chain reaction. The open reading frame of fLIGHT … WebThe protein content of animal organs is usually much higher than that of the blood plasma. Muscles, for example, contain about 30 percent protein, the liver 20 to 30 percent, and red blood cells 30 percent. Higher percentages of protein are found in hair, bones, and other organs and tissues with a low water content. WebProduct name Recombinant Human LIGHT Protein (Active) See all LIGHT/TNFSF14 proteins and peptides Biological activity Fully biologically active determined by the dose dependent proliferation of HUVEC. ED 50 is ≤0.83 ng/ml, corresponding to a specific activity of 1.2 x 10 6 units/mg. Purity >= 95 % HPLC. SDS PAGE>=95% Purity Endotoxin level talk therapy hypnotherapy